The Creative Review Annual is a 100-page special issue published by Centaur in the United Kingdom featuring the best of the previous year's content as well as unseen work. Each year a designer is commissioned to create a capital A for the cover. In response to the previous year's increasingly grand set-ups—including a twelve foot ice sculpture—I decided to work at a much smaller scale and teamed up with immunologist Frank Conrad to create this letter A at a cellular level."